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Small Molecule Inhibitors of NADPH Oxidase 4 (NOX4) Signaling
Application Small molecule inhibitors of NOX4 signaling with a wide array of therapeutic potential. Key Benefits Small molecule inhibitors of NOX4 signaling. Low cytotoxicity. Market Summary The NADPH oxidase 4 (NOX4) has gained considerable and growing attention during the past years because of its potential key involvement in a variety of...
Published: 12/1/2023       Contributor(s): Bernard Lassegue, Kathy Griendling, David Brown, Qian Xu, Osman Guner, J. Phillip Bowen, Amol Kulkarni, E. Blake Watkins
Small Molecule Derivatives of Solenopsin for Cancer Treatment
ApplicationSmall molecule analogs of the naturally-occurring compound solenopsin for the treatment of various cancers including melanoma and angiosarcoma.Key BenefitsAnalogs derived from a naturally-occurring alkaloid. Potential treatment of cancers for which there is a poor prognosis or low survival rate. Market SummaryPhosphoinositol-3 kinase (PI3K)...
Published: 1/25/2024       Contributor(s): Jack Arbiser, J. Phillip Bowen, E. Blake Watkins