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P81 & Q97 14-3-3 Polyclonal Antibodies
Application
Western blot
Immunoprecipitation
Specificity
Peptide sequences conserved within several human 14-3-3 protein subspecies
Subtype
Rabbit polyclonal
Technical Summary
Two rabbit sera identified as p81 and Q97 were made against synthetically synthesized peptides of 14-3-3 protein. The two antibodies are more specifically a beta-zeta...
Published: 12/20/2023
Contributor(s): David Pallas
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mMob3/Phocein (clone 16E2) Polyclonal Antibody
Application
Western Blot
Specificity
Human, Mouse, Rat
Subtype
Rabbit Polyclonal
Immunogen
KLH-Linked Peptide
Technical Summary
mMob3 also called Phocein (and was called mMob1 - see publication below) is a mammalian class II homolog of yeast MOB1 that appears to be a substrate for PP2A. In S. cerevisiae, MOB1 is an essential gene that is required...
Published: 12/20/2023
Contributor(s): David Pallas
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Polyclonal Antibodies Directed Against Human Flightless I Homolog
Applications
Western Blot
Immunofluorescence
Immunoprecipitation
Specificity
Human
Subtype
Polyclonal
Immunogen
(DP63/DP64) corresponding to residues 450-477 and 1152-1173 of Human Flightless I homolog
Technical Summary
Protein flightless-1 homolog (Flightless 1) is a member of the gelsolin family of actin-remodeling proteins. It interacts...
Published: 12/20/2023
Contributor(s): David Pallas
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RK117 Anti-yeast PME-1 (Protein Phosphatase Methylesterase-1) Polyclonal Antibody
Application
This antibody detects PME-1 in cell lysates and immunoprecipitates native protein.
Technical Summary
Dr. Pallas has made a polyclonal antibody to yeast PME-1, a protein methylesterase for which PP2A (protein phosphatase 2A) is a substrate. This antibody is raised against a PME-1 peptide. At this point there are no similar antibodies...
Published: 7/28/2023
Contributor(s): David Pallas
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Striatin Polyclonal Antibody RK16
Applications
Immunoprecipitation
Immunofluorescence
Immunoblotting
Specificity
A polyclonal antibody to striatin
Subtype
Anti-rabbit
Technical Summary
The inventor has made polyclonal antibodies to a striatin peptide. Striatin is a calmodulin (CaM)-binding proteins that forms a stable complex with PP2A A and PP2A C heterodimers....
Published: 12/7/2023
Contributor(s): David Pallas
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Protein Phosphatase 2A Regulatory A Subunit (4G7) Monoclonal and (R39) Polyclonal Antibodies
Applications
Immunoblotting
Immunofluorescence
Histochemistry
Specificity
Monoclonal and polyclonal antibodies that recognize the PP2A A subunit
Subtype
Anti-mouse
Technical Summary
The inventor has made monoclonal (4G7) and polyclonal (R39) antibodies to the PP2A A subunit peptide (DP32). Most A subunit antibodies available are polyclonal...
Published: 3/1/2024
Contributor(s): David Pallas
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S/G2 phase Nuclear Autoantigen (SG2NA) Monoclonal (S68) and Polyclonal (RK115) Antibodies
Applications
Immunoprecipitation
Immunofluorescence
Immunoblotting
Specificity
Monoclonal and polyclonal antibodies to SG2NA
Subtype
Anti-rabbit
Technical Summary
SG2NA is a calmodulin-binding proteins that form stable complexes with PP2A A and PP2C heterodimers. The inventor has made monoclonal and polyclonal antibodies to an SG2NA...
Published: 3/1/2024
Contributor(s): David Pallas
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4b7, 1d6, and 4e1 anti-PP2A Catalytic Subunit (Protein Phosphatase 2A) Methylation-Sensitive Monoclonal Antibodies
Applications
Immunoblo
Immunoblotting
Immunoprecipitation
Immunofluorescence
Histochemistry
Specificity
Monoclonal antibodies specific for the PP2A catalytic subunit.
Subtype
Anti-Mouse
Technical Summary
The inventor has developed an anti-PP2A C-terminal peptide monoclonal antibodies, specific for the PP2A C subunit, 1d6, 4b7, and 4e1....
Published: 3/1/2024
Contributor(s): David Pallas
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E37 anti-PME-1 (Protein Phosphatase Methylesterase-1) Polyclonal Antibody
ApplicationsAn antibody to detect mammalian PME-1 that can be used for immunoblotting and immunoflorescence and possibly histochemistryTechnical SummaryDr. Pallas has developed a polyclonal antibody to PME-1, a protein methylesterase for which PP2A (protein phosphatase 2A) is a substrate. PP2A is a highly conserved serine/threonine phosphatase involved...
Published: 7/28/2023
Contributor(s): David Pallas
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Protein Phosphatase 2A Demethylase Protein and DNA Sequences
Applications Can be used in assays to search for drugs that modulate protein phosphatase 2A (PP2A) methylesterase activity or to make recombinant protein to be used in assays. Such derivatives have potential application as anti-cancer and Alzheimer's treatment drugs. Technical Summary Protein phosphatase 2A (PP2A) is involved in the regulation of a...
Published: 12/20/2023
Contributor(s): David Pallas, Xian Xing Du
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