Implanted Passive Pressure Sensor Interrogated with (Ultra)-Sound (iPPSIS)
Application
Easy-to-use, short and long-term, minimally invasive, MR-safe approach for directly measuring the variation of intracranial pressure.
Key Benefits
A minimally invasive device that is compatible with MRI imaging for quantitatively measuring intracranial pressure.
A prototype has been developed showing the ability to measure shunt pressure...
Published: 3/1/2024
Contributor(s): David Myers, Nicholas Au Yong, Brooks Lindsey, Cecilia Alessandra Luna, Saeyoung (Sunny) Kim, Bowen Jing
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Reagents and Hardware for RNA Storage at Ambient Temperatures
Application
Simple and economical method for isolating and storing RNA from biological samples at room temperatures.
Key Benefits
Alternative, low-cost extraction method suitable for extracting RNA from biological samples for molecular analysis and disease diagnosis.
Eliminates the need for expensive proprietary materials, hazardous chemicals,...
Published: 3/1/2024
Contributor(s): Jesse Waggoner, David Myers, Sarah Hernandez, Dhruv Miglani
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Guiding the Cartilage Repair Microenvironment
Application
A novel method to improve the effectiveness of marrow-mediated cartilage repair.
Key Benefits
Enhances the efficacy of the marrow stimulation procedure for cartilage repair.
Priming the cartilage repair environment to enable subsequent healthy tissue growth.
Potential to become a one-step, implementable, and effective treatment for...
Published: 3/1/2024
Contributor(s): Sameh Labib, David Myers, Jay M. Patel, Maddie Hasson, Lorenzo Fernandes
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Biocompatible Nanoreporter for Measuring Fluidic Shear Stress
Application
A research tool for quantifying fluidic shear stress in vitro and in vivo.
Key Benefits
Directly measures sub-cellular shear stress from 0.5 dynes/cm2 to 100 dynes/cm2.
Can target specific ligands of interest.
Compatible with existing fluorescent approaches.
Flexible design allows for multiple modifications for a variety of...
Published: 3/1/2024
Contributor(s): David Myers, Yonggang Ke, Victor Pan, Shreyas Dahotre, Gabriel (Gabe) Kwong
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Mobile Application for Remote Screening of Abdominal Pain
ApplicationMobile application and program to remotely identify and assess severity of tenderness and abdominal pain.Key BenefitsAllows physician to replicate physical abdominal exam remotely.Eliminates distance barrier, increasing access to medical service.Potentially reduces need for in-person visits and costs.Market SummaryAbdominal (or stomach) pains...
Published: 7/28/2023
Contributor(s): Alexander Weiss, David Myers, Wilbur Lam
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Microfluidic Device for Increased Viral Transduction Efficiency
Application
Microfluidic chip device for facilitating high throughput viral transduction for gene therapy applications.
Key Benefits
Improves surface-to-volume ratio, allowing more efficient contact between lentiviruses and cells
Increases efficiency while maintaining cell viability of traditional methods.
Enables gene transfer for non-adherent...
Published: 1/10/2024
Contributor(s): Reginald Tran, Wilbur Lam, David Myers, Christopher Doering, H. (Harold) Trent Spencer
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Microfluidic Device Enhances Understanding of Clot Formation
Application
A microfluidic device for the measurement and quantification of the mechanical forces that occur during clot formation for use in hematology research or for diagnostic purposes.
Key Benefits
Is capable of measuring platelet-platelet interactions at the single cell level that is not possible with current tools.
Facilitates quick &...
Published: 11/6/2023
Contributor(s): David Myers, Wilbur Lam, Yongzhi Qiu
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Microfluidic Device for Delivery of Therapeutics into Cells
Application
Microfluidic slide with individual cell holders for use in microinjection procedures.
Key Benefits
Open system - compatible with other microinjection technologies and existing research instrumentation.
Compatible with both adherent and non-adherent cells.
Enables high-throughput and high-precision delivery of substances into cells,...
Published: 7/28/2023
Contributor(s): Wilbur Lam, David Myers, Zhengchun Peng, Gang Bao
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