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Repurposed Kinase Inhibitor for Treatment of Multidrug Resistant Tuberculosis
ApplicationProtein tyrosine kinase inhibitor (imatinib) used as a treatment to prevent multiple drug-resistant tuberculosis lethality and latent reactivation.Key BenefitsEffective against drug resistant strains of tuberculosis.May be used in combination with current first-line treatments of TB.Market SummaryTuberculosis (TB) is a chronic infectious...
Published: 11/27/2023       Contributor(s): Daniel Kalman
Small Molecules for the Treatment of Graft versus Host Disease
ApplicationAdministration of indole derivatives for the treatment of graft versus host disease.Key BenefitsDecreases incidence of GvHD after allogeneic transplantation.Does not create immuno-suppression in recipient.Market SummaryGraft versus host disease (GvHD) can arise following allogeneic transplantation, which is used for the treatment of diseases...
Published: 11/27/2023       Contributor(s): Daniel Kalman, Edmund Waller, Cynthia Giver, Alyson Swimm