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Multi-Target CCR5/CXCR4 Chemokine Compounds for the Treatment of HIV
Application Chemical compounds that bind to both CCR5 and CXCR4 chemokine GPCRs as therapeutics to block HIV entry and infection. Key Benefits Targets both chemokine receptors used for cell entry by HIV: CCR5 & CXCR4. Eliminates the requirement of a tropism pre-test used for drug administration of single chemokine agents. Does not interfere...
Published: 4/8/2024       Contributor(s): Bryan Cox, Lawrence (larry) Wilson, Anthony Prosser, James Snyder, Dennis Liotta