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Therapeutic Compounds Inhibiting DUSP5 and DUSP6 for Cardiomyocyte Proliferation and Cardiac Regeneration Application Therapeutics using siRNAs and small molecules to treat congenital heart defect and myocardial injuries. Key Benefits Reactivates cardiomyocyte (CM) cell replication, allowing regeneration of heart muscle after cardiac injuries. Therapeutic compounds may be administered for transient regeneration/repair of heart muscle after cardiac... Published: 7/28/2023       Contributor(s): Ahsan Husain, Nawazish Naqvi

Biomarker for Arteriovenous Fistula Dialysis Access Failure Application Plasma biomarker for the prediction of arteriovenous fistula (AVF) dialysis access failure during hemodialysis. Key Benefits Circulating chymase levels predict AVF failure in chronic hemodialysis patients. Proprietary antibody while other proprietary antibodies do not work as biomarkers. The ability to predict AVF failure may help... Published: 4/23/2024       Contributor(s): Haimanot Wasse, Ahsan Husain, Angel Rivera