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Compounds for Suppressing Fragile X Premutation rCGG Repreat-Mediated Toxicity
Application Compounds for the treatment of Fragile X-associated tremor/ataxia syndrome. Key Benefits 11 known, FDA approved drugs identified that reduced rCGG-mediated lethality to a certain degree. 3 of these drugs also rescued locomotion deficits. Technical Summary Fragile X syndrome (FXS) is the most common inheritable form of cognitive disabi...
Published: 2/24/2011       Inventor(s): Peng Jin, Abrar Qurashi